The next year, PacBio developed a new method to allow multiple sequencing passes on the same DNA molecule. Double stranded DNA templates were ligated to two single stranded adapters, creating what the company called a “SMRTbell template.” Sequencing began at a primer on one of the adaptors and could proceed multiple times per molecule due to circularization, in a process called rolling-circle amplification. This helped reduce PacBio’s error rates significantly.
Конфликт США с Ираном назвали ударом для Украины14:58
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По мнению экономиста Михаила Беляева, одним из наиболее мрачных последствий ближневосточного конфликта может стать падение темпов роста мировых экономик. С другой стороны, России, возможно, уже не придется продавать нефть с большими скидками.
They said there was a risk of a two-tier system, potentially pushing up prices in outlets that still accepted cash and creating a poverty premium for those who best budgeted using cash.